If you arrive in Rome by air, from Fiumicino's Leonardo da Vinci Airport you may take the direct train to Termini. Exit Termini station from the Via Marsala side, walk down Via Marghera right up to the end of the road, then turn left in Via Palestro. Hotel Prince Galles Rome is at number 72.
From Ciampino Airport there are several frequent and convenient bus services.
Very close to the hotel you will find:
Termini Station is the terminus for many bus and tram lines that lead to most of Rome's central areas and its outskirts, as well as of the "Open Bus" tourist lines that go through the most interesting tourist and social venues.